The IFN-gamma Antibody (PAC049690) is a polyclonal antibody specifically designed for research involving interferon-gamma (IFN-gamma), a key cytokine involved in immune response regulation. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications including Western blot and immunohistochemistry.IFN-gamma is known for its role in activating immune cells and modulating the immune response to infections, tumors, and autoimmune diseases. The IFN-gamma Antibody binds specifically to IFN-gamma protein, allowing for precise detection and analysis in a variety of cell types.
This makes it an invaluable tool for researchers studying immunology, infectious diseases, and cancer.Understanding the mechanisms by which IFN-gamma functions is essential for developing therapies that can enhance immune responses or regulate inflammation in various disease contexts. With its high specificity and reactivity, the IFN-gamma Antibody is a crucial asset for researchers seeking to further explore the role of IFN-gamma in immune regulation and disease pathogenesis.
Antibody Name:
IFNG Antibody (PACO49690)
Antibody SKU:
PACO49690
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Bovine
Immunogen:
Recombinant Bovine Interferon γ protein (24-166AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: IFNG antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. predicted band size: 20 kDa. observed band size: 20 kDa..
Background:
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Synonyms:
Interferon γ (BoIFNG) (IFN-gamma), IFNG
UniProt Protein Function:
Function: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.