The IFNAR2 Polyclonal Antibody (CAB1769) is a vital tool for researchers studying the interferon-alpha/beta receptor 2 (IFNAR2) protein. IFNAR2 is a key player in the immune response to viral infections, as it is involved in the signaling pathway triggered by interferons. By binding specifically to IFNAR2, this antibody allows for the detection and analysis of the protein in a variety of cell types.Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. Its specificity for IFNAR2 makes it an invaluable asset for studies in virology, immunology, and infectious diseases.
Understanding the role of IFNAR2 in the immune response can provide insights into how the body defends itself against viruses and may lead to the development of novel antiviral therapies.Overall, the IFNAR2 Polyclonal Antibody (CAB1769) is a reliable tool for researchers looking to uncover the mechanisms behind the body's response to viral infections and the potential for targeting IFNAR2 in the development of new treatments.
Product Name:
IFNAR2 Rabbit Polyclonal Antibody
SKU:
CAB1769
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-243 of human IFNAR2 (NP_997468.1).
Membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
58kDa
Observed MW:
95kDa
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45.
Purification Method:
Affinity purification
Gene ID:
3455
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IFNAR2 Rabbit pAb (CAB1769) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
