The IFNAR1 Polyclonal Antibody (CAB18594) is a valuable tool for researchers investigating the IFNAR1 protein, a critical receptor involved in the cellular response to interferons. This rabbit polyclonal antibody is highly specific and sensitive, making it ideal for use in a variety of research applications such as Western blot, immunohistochemistry, and flow cytometry.IFNAR1 plays a key role in the regulation of immune response to viral infections and has been implicated in autoimmune diseases and cancer. By targeting IFNAR1 in research studies, scientists can gain a better understanding of the mechanisms underlying these diseases and potentially develop new therapeutic interventions.
With its high reactivity and specificity, the IFNAR1 Polyclonal Antibody (CAB18594) is a valuable tool for researchers working in the fields of immunology, virology, and oncology. By enabling the detection and analysis of IFNAR1 expression in various cell types, this antibody contributes to advancing our knowledge of immune regulation and disease pathology.
Product Name:
IFNAR1 Rabbit Polyclonal Antibody
SKU:
CAB18594
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 470-557 of human IFNAR1 (NP_000620.2).
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
Purification Method:
Affinity purification
Gene ID:
3454
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IFNAR1 Rabbit pAb (CAB18594) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
