The IFNAR1 Rabbit Monoclonal Antibody is a cutting-edge tool for researchers studying the interferon-alpha/beta receptor 1 (IFNAR1), a key component in the body's immune response to viral infections. This antibody is meticulously produced using rabbit monoclonal technology, ensuring high specificity and sensitivity in detecting IFNAR1 protein in human samples.IFNAR1 is essential for the activation of antiviral pathways triggered by interferons, making it a crucial player in the body's defense against viral infections. By targeting IFNAR1, researchers can better understand the mechanisms behind viral immune responses and potentially develop new therapies for viral diseases.
Validated for use in Western blot applications, the IFNAR1 Rabbit Monoclonal Antibody facilitates accurate detection and analysis of IFNAR1 protein levels in various cell types. Its versatility and reliability make it an invaluable tool for studies in virology, immunology, and infectious disease research.Overall, the IFNAR1 Rabbit Monoclonal Antibody offers researchers a powerful tool to delve deeper into the intricate workings of the immune system and develop innovative strategies for combating viral infections.
Product Name:
IFNAR1 Rabbit Monoclonal Antibody
SKU:
CAB0575
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 458-557 of human IFNAR1 (P17181).
Hep G2,A-549,NIH/3T3,Mouse brain,Rat lung,Rat liver
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Single-pass type I membrane protein.
Calculated MW:
64kDa
Observed MW:
90-130kDa
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
Purification Method:
Affinity purification
Gene ID:
3454
Clone Number:
ARC0262
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IFNAR1 Rabbit mAb (CAB0575) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
