The IFNAR1 Polyclonal Antibody (CAB1715) is an essential tool for researchers studying IFNAR1, a crucial protein involved in the Type I interferon signaling pathway. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the IFNAR1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology and virology research.IFNAR1, or interferon-alpha/beta receptor subunit 1, plays a vital role in the immune response to viral infections and other pathogens.
Understanding the function of IFNAR1 is crucial for investigating host immune defense mechanisms and developing targeted therapies for infectious diseases. The IFNAR1 Polyclonal Antibody is a valuable tool for researchers investigating the role of IFNAR1 in antiviral immunity and inflammatory responses, providing insights that may lead to the development of new treatments for infectious diseases.
Product Name:
IFNAR1 Rabbit Polyclonal Antibody
SKU:
CAB1715
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-290 of human IFNAR1 (NP_000620.2).
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
Purification Method:
Affinity purification
Gene ID:
3454
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using IFNAR1 Rabbit pAb (CAB1715) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
