The IFNA5 Polyclonal Antibody (PACO62307) is a valuable tool for researchers studying the interferon alpha family member 5 (IFNA5) protein. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting.IFNA5 is a member of the interferon alpha family, which plays a key role in the immune response to viral infections and cancer. By targeting IFNA5 with this antibody, researchers can detect and analyze the protein in different cell types, aiding in the study of immunology and cancer research.
The IFNA5 Polyclonal Antibody is essential for understanding the function of IFNA5 and its potential as a therapeutic target in diseases involving immune dysfunction, such as viral infections and cancer. Its ability to specifically bind to IFNA5 makes it a valuable tool for investigations into the role of this protein in various biological processes.
Antibody Name:
IFNA5 Antibody (PACO62307)
Antibody SKU:
PACO62307
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Interferon alpha-5 protein (52-73AA)
IHC image of PACO62307 diluted at 1:100 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Produced by macrophages, IFN-α have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
IFNA5: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family.Protein type: Secreted, signal peptide; Cytokine; SecretedChromosomal Location of Human Ortholog: 9p22Cellular Component: extracellular region; extracellular spaceMolecular Function: cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor bindingBiological Process: adaptive immune response; B cell differentiation; B cell proliferation; blood coagulation; cytokine and chemokine mediated signaling pathway; humoral immune response; innate immune response; natural killer cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response
