The IFN-Beta Monoclonal Antibody is a valuable tool for researchers studying interferon-beta, a key player in the immune response to viral infections and autoimmune diseases. This antibody, generated in mice, is highly specific to human IFN-Beta and is validated for use in various applications such as ELISA, Western blot, and immunohistochemistry.Interferon-beta is a type I interferon that helps to regulate the immune response by promoting anti-viral activities and modulating inflammation. Research on IFN-Beta is essential for understanding its role in autoimmune diseases like multiple sclerosis and systemic lupus erythematosus, as well as its potential as a therapeutic target for these conditions.
By utilizing the IFN-Beta Monoclonal Antibody, researchers can effectively study the expression and function of IFN-Beta in different cell types and tissues, paving the way for new insights into immune regulation and the development of targeted therapies for immune-related disorders.
Product Name:
IFN-beta Monoclonal Antibody
SKU:
CAB22740
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of mouse IFN-beta (NP_034640.1)
63kDa (C-hFc&His taged Active Recombinant Mouse IFN-beta Protein)，24kDa/26kDa(Endogenous)
Enables cytokine activity and type I interferon receptor binding activity. Involved in B cell proliferation; cellular response to virus; and type I interferon signaling pathway. Acts upstream of or within several processes, including cellular response to organic cyclic compound; defense response to other organism; and negative regulation of osteoclast differentiation. Located in extracellular space. Is expressed in embryo and liver. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFNB1 (interferon beta 1).
Purification Method:
Affinity purification
Gene ID:
15977
Clone Number:
ARC58590
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of recombinant Mouse IFN-beta Protein using IFN-beta Rabbit mAb (CAB22740) at 1:6000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 10ng/5ng/1ng per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
