UniProt Protein Function: | IFITM5: Plays a role in bone mineralization. Belongs to the CD225/Dispanin family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11p15.5Cellular Component: integral to plasma membraneBiological Process: bone mineralizationDisease: Osteogenesis Imperfecta, Type V |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). [provided by RefSeq, Aug 2012] |
UniProt Code: | A6NNB3 |
NCBI GenInfo Identifier: | 158705851 |
NCBI Gene ID: | 387733 |
NCBI Accession: | A6NNB3.1 |
UniProt Secondary Accession: | A6NNB3 |
UniProt Related Accession: | A6NNB3 |
Molecular Weight: | 14,378 Da |
NCBI Full Name: | Interferon-induced transmembrane protein 5 |
NCBI Synonym Full Names: | interferon induced transmembrane protein 5 |
NCBI Official Symbol: | IFITM5Â Â |
NCBI Official Synonym Symbols: | OI5; BRIL; DSPA1; Hrmp1; fragilis4Â Â |
NCBI Protein Information: | interferon-induced transmembrane protein 5 |
UniProt Protein Name: | Interferon-induced transmembrane protein 5 |
UniProt Synonym Protein Names: | Bone-restricted interferon-induced transmembrane protein-like protein; BRIL; Dispanin subfamily A member 1; DSPA1 |
Protein Family: | Interferon-induced transmembrane protein |
UniProt Gene Name: | IFITM5Â Â |
UniProt Entry Name: | IFM5_HUMAN |