The IFITM3 Polyclonal Antibody (CAB13070) is a valuable tool for researchers studying the interferon-induced transmembrane protein 3 (IFITM3), a key player in antiviral immune responses. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications.IFITM3 is known for its role in restricting the entry of various viruses into host cells, making it a crucial component of the innate immune response. By targeting IFITM3, researchers can gain insights into the mechanisms of viral pathogenesis and potentially develop new antiviral strategies.
The IFITM3 Polyclonal Antibody enables reliable detection and analysis of IFITM3 expression in a variety of cell types, making it a versatile tool for studies in virology, immunology, and infectious diseases. Its high specificity and sensitivity make it an essential asset for researchers investigating the intricate interplay between viruses and the host immune system.
Product Name:
[KO Validated] IFITM3 Rabbit Polyclonal Antibody
SKU:
CAB13070
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-133 of human IFITM3 (NP_066362.2).
Cell membrane, Late endosome membrane, Lysosome membrane, Single-pass type II membrane protein.
Calculated MW:
15kDa
Observed MW:
15kDa
Interferon-induced transmembrane (IFITM) proteins are a family of interferon induced antiviral proteins. The family contains five members, including IFITM1, IFITM2 and IFITM3 and belong to the CD225 superfamily. The protein encoded by this gene restricts cellular entry by diverse viral pathogens, such as influenza A virus, Ebola virus and Sars-CoV-2.
Purification Method:
Affinity purification
Gene ID:
10410
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using [KO Validated] IFITM3 Rabbit pAb (CAB13070) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
