The IFITM2 Polyclonal Antibody (CAB15133) is a valuable tool for researchers studying IFITM2, a cell membrane protein with key roles in immune response and viral infection. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blotting and immunofluorescence applications.IFITM2, also known as interferon-induced transmembrane protein 2, is involved in the regulation of viral entry into host cells and plays a crucial role in innate immune defense mechanisms. Its expression has been linked to antiviral activity against a variety of pathogens, making it an attractive target for investigating viral pathogenesis and host-pathogen interactions.
By utilizing the IFITM2 Polyclonal Antibody, researchers can effectively detect and analyze IFITM2 protein expression in various cell types, facilitating deeper insights into its function and potential therapeutic applications. This antibody is essential for studies in virology, immunology, and infectious disease research, providing a valuable tool for understanding the molecular mechanisms underlying immune responses and viral infections.
Product Name:
IFITM2 Rabbit Polyclonal Antibody
SKU:
CAB15133
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFITM2 (NP_006426.2).
Interferon-induced transmembrane (IFITM) proteins are a family of interferon induced antiviral proteins. The family contains five members, including IFITM1, IFITM2 and IFITM3 and belong to the CD225 superfamily. The protein encoded by this gene restricts cellular entry by diverse viral pathogens, such as influenza A virus, Ebola virus and Sars-CoV-2.
Purification Method:
Affinity purification
Gene ID:
10581
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using IFITM2 Rabbit pAb (CAB15133) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
