The IFITM1 Polyclonal Antibody (CAB4228) is a vital tool for researchers studying IFITM1, a cellular protein with roles in immune response and viral infection. This antibody has been developed using rabbits and is highly specific for human samples, making it suitable for a variety of research applications, including Western blotting.IFITM1, also known as interferon-induced transmembrane protein 1, is involved in regulating cellular processes in response to viral infections. It plays a crucial role in the immune system's defense against pathogens and has been linked to various diseases, including cancer and infectious diseases.
By targeting the IFITM1 protein, researchers can gain insights into its function and its potential as a therapeutic target.This polyclonal antibody enables the detection and analysis of IFITM1 in different cell types, making it a valuable tool for immunology, infectious disease, and cancer research. By studying the role of IFITM1, researchers can better understand its impact on immune responses and potentially develop new treatments for diseases influenced by this protein.
Product Name:
IFITM1 Rabbit Polyclonal Antibody
SKU:
CAB4228
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-125 of human CD225/IFITM1 (NP_003632.3).
Interferon-induced transmembrane (IFITM) proteins are a family of interferon induced antiviral proteins. The family contains five members, including IFITM1, IFITM2 and IFITM3 that belong to the CD225 superfamily. The protein encoded by this gene restricts cellular entry by diverse viral pathogens, such as influenza A virus, Ebola virus and Sars-CoV-2.
Purification Method:
Affinity purification
Gene ID:
8519
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells, using CD225/IFITM1 Rabbit pAb (CAB4228) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
