Description
Product Name: | IFIH1 Polyclonal Antibody |
SKU: | CAB24868 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 277-490 of human IFIH1 (NP_071451.2). |
Sequence: | SNMG SDSG TMGS DSDE ENVA ARAS PEPE LQLR PYQM EVAQ PALE GKNI IICL PTGS GKTR VAVY IAKD HLDK KKKA SEPG KVIV LVNK VLLV EQLF RKEF QPFL KKWY RVIG LSGD TQLK ISFP EVVK SCDI IIST AQIL ENSL LNLE NGED AGVQ LSDF SLII IDEC HHTN KEAV YNNI MRHY LMQK LKNN RLKK ENKP VIPL PQIL GLTA S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | IFIH1; AGS7; Hlcd; IDDM19; MDA-5; MDA5; RLR-2; SGMRT1; interferon induced with helicase C domain 1 |
Positive Sample: | THP-1 treated by LPS |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 25kDa/116kDa |
Observed MW: | 140kDa |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.
Purification Method: | Affinity purification |
Gene ID: | 64135 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |