The IFI30 Polyclonal Antibody (AB12003) is a versatile tool for researchers studying the IFI30 protein, also known as Gamma Interferon-Inducible Lysosomal Thiol Reductase (GILT). This antibody, derived from rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in various experimental techniques, including Western blotting and immunohistochemistry.IFI30/GILT is involved in the immune response by aiding in the breakdown of foreign antigens within lysosomes, thereby facilitating antigen presentation and T cell activation.
Its role in antigen processing and presentation makes it a key player in adaptive immunity and a potential target for therapeutic interventions in infectious diseases, autoimmunity, and cancer.With its ability to specifically bind to IFI30 proteins in various cell types, this polyclonal antibody enables researchers to analyze the expression and regulation of IFI30 in different biological contexts, providing valuable insights into immune responses and disease pathogenesis. Unlock the potential of IFI30 research with the IFI30 Polyclonal Antibody.
Product Name:
IFI30 Rabbit Polyclonal Antibody
SKU:
CAB12995
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human IFI30 (NP_006323.2).
The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.
Purification Method:
Affinity purification
Gene ID:
10437
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using IFI30 Rabbit pAb (CAB12995) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 30s.
