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IFI16 Polyclonal Antibody (CAB24865)

SKU:
CAB24865
€129
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Description

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Product Name:IFI16 Polyclonal Antibody
SKU:CAB24865
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 500-785 of human IFI16 (NP_001351796.1).
Sequence:KSED TISK MNDF MRMQ ILKE GSHF PGPF MTSI GPAE SHPH TPQM PPST PSSS FLTT LKPR LKTE PEEV SIED SAQS DLKE VMVL NATE SFVY EPKE QKKM FHAT VATE NEVF RVKV FNID LKEK FTPK KIIA IANY VCRN GFLE VYPF TLVA DVNA DRNM EIPK GLIR SASV TPKI NQLC SQTK GSFV NGVF EVHK KNVR GEFT YYEI QDNT GKME VVVH GRLT TINC EEGD KLKL TCFE LAPK SGNT GELR SVIH SHIK VIKT RKNK KDIL NPDS SMET SPDF FF
Tested Applications:WB FC ELISA
Recommended Dilution:WB,1:500 - 1:1000 FC,1:500 - 1:1000
Synonyms:IFI16; IFNGIP1; PYHIN2; gamma-interferon-inducible protein 16
Positive Sample:Daudi
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:75kDa/82kDa/88kDa
Observed MW:95kDa,98kDa

This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:3428
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using IFI16 Rabbit pAb (CAB24865) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC): MCF7.Exposure time: 0.5s.

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