IFI16 Rabbit Polyclonal Antibody (CAB14002)
- SKU:
- CAB14002
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | IFI16 Rabbit Polyclonal Antibody |
SKU: | CAB14002 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IFI16 (NP_001351796.1). |
Sequence: | MGKK YKNI VLLK GLEV INDY HFRM VKSL LSND LKLN LKMR EEYD KIQI ADLM EEKF RGDA GLGK LIKI FEDI PTLE DLAE TLKK EKLK VKGP ALSR KRKK EVDA TSPA PSTS STVK TEGA EATP GAQK RKKS TKEK AGPK GSKV SEEQ TQPP SPAG AGMS TAMG RSPS PKTS LSAP PNSS STEN PKTV AKCQ VTPR RNVL QKRP VIVK VLST TKPF EYET PEME KKIM FHAT VATQ TQFF HVKV LNTS LKEK FNGK KIII ISDY LEYD SLLE VNEE STVS EAGP NQTF EVPN KIIN RAKE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | PYHIN2; IFNGIP1; IFI16 |
Positive Sample: | U-87MG,Daudi |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 88kDa |
Observed MW: | 85-98kDa |
This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3428 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |