Description
Product Name: | IFI16 Polyclonal Antibody |
SKU: | CAB24865 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-785 of human IFI16 (NP_001351796.1). |
Sequence: | KSED TISK MNDF MRMQ ILKE GSHF PGPF MTSI GPAE SHPH TPQM PPST PSSS FLTT LKPR LKTE PEEV SIED SAQS DLKE VMVL NATE SFVY EPKE QKKM FHAT VATE NEVF RVKV FNID LKEK FTPK KIIA IANY VCRN GFLE VYPF TLVA DVNA DRNM EIPK GLIR SASV TPKI NQLC SQTK GSFV NGVF EVHK KNVR GEFT YYEI QDNT GKME VVVH GRLT TINC EEGD KLKL TCFE LAPK SGNT GELR SVIH SHIK VIKT RKNK KDIL NPDS SMET SPDF FF |
Tested Applications: | WB FC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 FC,1:500 - 1:1000 |
Synonyms: | IFI16; IFNGIP1; PYHIN2; gamma-interferon-inducible protein 16 |
Positive Sample: | Daudi |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 75kDa/82kDa/88kDa |
Observed MW: | 95kDa,98kDa |
This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3428 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |