The IER3 Polyclonal Antibody (CAB8566) is a valuable tool for researchers studying IER3, a protein involved in cell stress response and apoptosis regulation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the IER3 protein, this antibody enables researchers to detect and analyze the expression of IER3 in various cell types, making it ideal for studies in cell biology and cancer research.IER3, also known as Immediate Early Response 3, plays a crucial role in regulating cellular responses to various stressors, such as DNA damage and oxidative stress.
Its involvement in apoptosis and cell cycle regulation makes it a potential target for therapeutic development in conditions like cancer and neurodegenerative diseases. By understanding the function of IER3, researchers can gain insights into the mechanisms of cell survival and death pathways, leading to potential novel treatment strategies.
Product Name:
IER3 Rabbit Polyclonal Antibody
SKU:
CAB8566
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IER3 (NP_003888.2).
This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.
Purification Method:
Affinity purification
Gene ID:
8870
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using IER3 Rabbit pAb (CAB8566) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
