The IER2 Polyclonal Antibody (PACO28774) is a valuable tool for researchers studying IER2, a stress-inducible gene that plays a significant role in cell survival and apoptosis. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting IER2 in human samples, making it suitable for use in Western blot applications. By binding to the IER2 protein, this antibody enables researchers to study its expression and function in various cell types, making it an ideal choice for investigations in cell biology and cancer research.IER2, also known as immediate early response 2, is a key player in cellular stress responses and is involved in regulating gene expression in response to various stimuli.
Its involvement in apoptosis and cell survival pathways makes it a valuable target for research related to cancer, neurodegenerative diseases, and other conditions characterized by dysregulated cell death processes. Understanding the role of IER2 can provide valuable insights into the mechanisms underlying these diseases and may lead to the development of novel therapeutic strategies targeting this protein.
Antibody Name:
IER2 Antibody (PACO28774)
Antibody SKU:
PACO28774
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Immediate early response gene 2 protein (1-223AA)
DNA-binding protein that seems to act as a transcription factor (PubMed:19584537). Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By similarity). May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity). Promotes cell motility, seems to stimulate tumor metastasis (PubMed:22120713).
Synonyms:
Immediate early response gene 2 protein (Protein ETR101), IER2, ETR101 PIP92
UniProt Protein Function:
IER2: Belongs to the IER family.Protein type: Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 19p13.2Cellular Component: cytoplasm
