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IDS Monoclonal Antibody [PAT6H4AT] (CPAB0276)

SKU:
CPAB0276
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT6H4AT
Applications:
WB
ELISA
FC
€149

Description

system_update_alt Datasheet

IDS Monoclonal Antibody [PAT6H4AT] (CPAB0276)

The IDS Antibody (CPAB0276) is a high-quality polyclonal antibody designed for researchers studying the IDS protein, which is involved in the catabolism of dermatan sulfate and chondroitin sulfate. This antibody, produced in rabbits, has been rigorously validated for use in Western blot applications and is highly reactive with human samples.The IDS Antibody binds specifically to the IDS protein, allowing for accurate detection and analysis in a variety of cell types. Its reliability and specificity make it an essential tool for studies in biochemistry, molecular biology, and drug development related to lysosomal storage disorders and mucopolysaccharidoses.

The IDS Antibody is a valuable resource for researchers aiming to better understand the role of IDS in diseases such as Hunter syndrome and Hurler syndrome. By elucidating the function of IDS in these conditions, scientists can potentially develop targeted therapies to improve patient outcomes and quality of life. Order your IDS Antibody today to advance your research in the field of lysosomal storage disorders.

Product Name:IDS Antibody
Product Sku:CPAB0276
Size:5μg
Host Species:Mouse
Immunogen:Anti-human IDS mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IDS protein 26-55 amino acids  purified from Ecoli.
Clone:PAT6H4AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:IDS antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:Iduronate 2-Sulfatase also known as IDS, belongs to the highly-conserved sulfatase family of enzymes which catalyze the hydrolysis of O-sulfate and N-salfate esters from a variety of substrates. IDS is essential for the lysosomal degradation of the glycosaminoglycans (GAG) heparan sulfate as well as dermatan sulfate. Furthermore, IDS hydrolyzes the 2-sulfate group of the IDS units of the GAG.
Synonyms:Iduronate 2-Sulfatase, Alpha-L-Iduronate Sulfate Sulfatase, Idursulfase, SIDS, Iduronate 2-Sulfatase 14 KDa Chain, Iduronate 2-Sulfatase 42 KDa Chain, Hunter Syndrome, EC 3.1.6.13, MPS2, Iduronate 2-sulfatase, Alpha-L-iduronate sulfate sulfatase, Idursulfase.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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