IDH3A Rabbit Polyclonal Antibody (CAB14650)
- SKU:
- CAB14650
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
Product Name: | IDH3A Rabbit Polyclonal Antibody |
SKU: | CAB14650 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-366 of human IDH3A (NP_005521.1). |
Sequence: | TGGV QTVT LIPG DGIG PEIS AAVM KIFD AAKA PIQW EERN VTAI QGPG GKWM IPSE AKES MDKN KMGL KGPL KTPI AAGH PSMN LLLR KTFD LYAN VRPC VSIE GYKT PYTD VNIV TIRE NTEG EYSG IEHV IVDG VVQS IKLI TEGA SKRI AEFA FEYA RNNH RSNV TAVH KANI MRMS DGLF LQKC REVA ESCK DIKF NEMY LDTV CLNM VQDP SQFD VLVM PNLY GDIL SDLC AGLI GGLG VTPS GNIG ANGV AIFE SVHG TAPD IAGK DMAN PTAL LLSA VMML RHMG LFDH AARI EAAC FATI KDGK SLTK DLGG NAKC SDFT EEIC RRVK DLD |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | RP90; IDH3A |
Positive Sample: | Raji,NIH/3T3,Mouse brain,Mouse heart,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 40kDa |
Observed MW: | 40kDa |
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Purification Method: | Affinity purification |
Gene ID: | 3419 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |