The ID3 Polyclonal Antibody (CAB5375) is a valuable tool for researchers studying the ID3 protein, a key regulator of cell differentiation and proliferation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the ID3 protein, this antibody allows for precise detection and analysis of ID3 expression in a variety of cell types, making it ideal for research in the fields of developmental biology and cancer.ID3, also known as inhibitor of DNA binding 3, plays a crucial role in controlling cell fate determination and is involved in various biological processes, including cell cycle regulation and maintenance of stem cell populations.
Dysregulation of ID3 has been linked to cancer development and progression, making it a promising target for therapeutic intervention. By studying the functions of ID3 using this antibody, researchers can gain insight into potential mechanisms underlying tumorigenesis and identify new strategies for cancer treatment.
Product Name:
ID3 Rabbit Polyclonal Antibody
SKU:
CAB5375
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human ID3 (NP_002158.3).
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts.
Purification Method:
Affinity purification
Gene ID:
3399
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Rat brain using ID3 Rabbit pAb (CAB5375) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
