The ID2 Polyclonal Antibody (CAB0996) is a valuable tool for researchers studying the ID2 protein, a transcription factor involved in various cellular processes, such as cell differentiation, proliferation, and survival. This antibody, produced in rabbits, exhibits high reactivity specifically with human samples and has been validated for use in Western blot applications.ID2 is known to play a critical role in developmental processes, including neurogenesis, myogenesis, and lymphopoiesis. Dysregulation of ID2 expression has been implicated in various diseases, including cancer and immune disorders. Therefore, studying the role of ID2 in these contexts is of great interest to researchers aiming to uncover new therapeutic targets and treatment strategies.
With its high specificity and sensitivity, the ID2 Polyclonal Antibody (CAB0996) enables accurate detection and analysis of ID2 protein levels in a variety of cell types. Its versatility makes it an essential tool for studies in developmental biology, cancer research, and immunology. By gaining insights into the function of ID2, researchers can advance our understanding of disease mechanisms and potentially identify novel therapeutic interventions.
Product Name:
ID2 Rabbit Polyclonal Antibody
SKU:
CAB0996
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 75-134 of human ID2 (NP_002157.2).
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.
Purification Method:
Affinity purification
Gene ID:
3398
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using ID2 Rabbit pAb (CAB0996) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
