The ID1 Polyclonal Antibody (CAB8432) is an essential tool for researchers studying ID1, a transcription factor known for its role in cancer progression and stem cell maintenance. This antibody, produced in rabbits, has high specificity for human samples and is validated for use in various applications, including Western blot and immunohistochemistry.ID1 is a key player in promoting tumor growth, invasion, and metastasis, making it a promising target for cancer therapy research. By targeting ID1, researchers can gain valuable insights into the molecular mechanisms underlying cancer development and identify potential therapeutic strategies to combat this deadly disease.
Furthermore, ID1 has also been implicated in stem cell regulation, suggesting its importance in tissue regeneration and repair. The ID1 Polyclonal Antibody offers researchers a valuable tool to investigate the role of ID1 in stem cell biology and potentially harness its regenerative potential for therapeutic purposes.Overall, the ID1 Polyclonal Antibody (CAB8432) is a valuable resource for researchers seeking to unravel the complexities of ID1 biology and develop novel approaches for the treatment of cancer and other diseases.
Product Name:
ID1 Rabbit Polyclonal Antibody
SKU:
CAB8432
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-155 of human ID1 (NP_002156.2).
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3397
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat heart, using ID1 antibody (CAB8432) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:1000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00020).Exposure time: 60s.