The ICOS Ligand Polyclonal Antibody (CAB7080) is a valuable tool for researchers studying the immune co-stimulatory molecule ICOS Ligand. This antibody is raised in rabbits and has been validated for use in Western blot applications, providing reliable detection and analysis of ICOS Ligand in human samples.ICOS Ligand, also known as Inducible T-cell Co-Stimulator Ligand, plays a crucial role in regulating T cell activation and immune responses. By binding to the ICOS receptor on T cells, ICOS Ligand activates signaling pathways that promote T cell proliferation and cytokine production, ultimately enhancing immune responses.
Research into ICOS Ligand is important for understanding immune regulation and developing novel immunotherapies for diseases like cancer and autoimmune disorders.The ICOS Ligand Polyclonal Antibody (CAB7080) offers high specificity and sensitivity, making it an ideal tool for studying the expression and function of ICOS Ligand in various biological contexts. Its versatility and reliability make it a valuable asset for immunology and cancer research projects seeking to elucidate the roles of ICOS Ligand in immune modulation and disease pathogenesis.
Product Name:
ICOSL Rabbit Polyclonal Antibody
SKU:
CAB7080
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-256 of human ICOSL (NP_056074.1).
Enables identical protein binding activity. Predicted to be involved in T cell receptor signaling pathway and positive regulation of interleukin-4 production. Located in cytoplasmic ribonucleoprotein granule and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
23308
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded Human skin carcinoma using ICOSL Rabbit pAb (CAB7080) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
