The ICOS Polyclonal Antibody (CAB1811) offered by Assay Genie is a valuable tool for research involving the study of the Inducible T-cell COStimulator (ICOS) protein. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.ICOS is a co-stimulatory molecule expressed on activated T-cells and plays a key role in regulating T-cell activation and immune response. The ICOS Polyclonal Antibody allows for the detection and analysis of ICOS protein expression in various cell types, providing valuable insights for immunological studies and cancer research.
Understanding the function and regulation of ICOS is important in the development of immunotherapies and treatments for autoimmune diseases, inflammatory conditions, and cancer. The ICOS Polyclonal Antibody from Assay Genie enables researchers to delve deeper into the role of ICOS in immune responses, paving the way for advancements in disease prevention and treatment strategies.
Product Name:
ICOS/CD278 Rabbit Polyclonal Antibody
SKU:
CAB1811
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-140 of human ICOS/CD278 (NP_036224.1).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
23kDa
Observed MW:
30-40kDa
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
Purification Method:
Affinity purification
Gene ID:
29851
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ICOS/CD278 Rabbit pAb (CAB1811) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
