The ICK Polyclonal Antibody (CAB7783) is a valuable tool for researchers studying the ICK protein, a key player in cell cycle regulation and cancer biology. This polyclonal antibody, raised in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blot analysis. By targeting the ICK protein, this antibody enables accurate detection and analysis of ICK expression in different cell types, making it an essential resource for studies in cancer research and cell biology.ICK, also known as inducible citron kinase, is a critical regulator of cell division and proliferation, making it a promising target for research into cancer and other proliferative disorders.
Understanding the role of ICK in cell cycle control is essential for developing targeted therapies that could potentially disrupt cancer cell growth and proliferation. By studying the activity of ICK, researchers can gain important insights into the mechanisms underlying cancer development and identify new therapeutic approaches for treating this devastating disease.
Product Name:
ICK Rabbit Polyclonal Antibody
SKU:
CAB7783
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ICK (NP_057597.2).
Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
Purification Method:
Affinity purification
Gene ID:
22858
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ICK antibody (CAB7783) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
