The ICE1 Antibody (PAC047262) is a polyclonal antibody specifically designed for research involving ICE1, a transcription factor that plays a critical role in cold stress response in plants. This antibody, raised in rabbits, is highly reactive with plant samples and has been validated for use in various applications, including Western blot and immunohistochemistry.ICE1, also known as Inducer of CBF Expression 1, is a key regulator of cold stress signaling pathways in plants, controlling the expression of genes responsible for cold tolerance. Research on ICE1 is vital for understanding how plants respond to cold stress, which is crucial for improving crop yields and overall plant health in cold climates.
The ICE1 Antibody enables the precise detection and analysis of ICE1 protein levels in plant samples, providing researchers with valuable insights into the mechanisms behind cold stress response in plants. Its high specificity and sensitivity make it an ideal tool for studies in plant biology, agriculture, and environmental science. Unlocking the secrets of ICE1 could lead to innovative strategies for increasing cold tolerance in crops and enhancing agricultural productivity in challenging environments.
Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO47262 at dilution of 1:100.
Western Blot. Positive WB detected in: Mouse brain tissue. All lanes: ICE1 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 68 kDa. Observed band size: 68 kDa.
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO47262 at dilution of 1:100.
Background:
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies.
Synonyms:
Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1), ICE1, KIAA0947
UniProt Protein Function:
ICE1: protein of unknown function.Protein type: Unknown functionChromosomal Location of Human Ortholog: 5p15.32Cellular Component: Cajal body; nucleoplasm; transcription elongation factor complexMolecular Function: protein binding; protein homodimerization activityBiological Process: positive regulation of protein complex assembly; positive regulation of transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter
