The ICAM1 Polyclonal Antibody (CAB5597) is a valuable tool for researchers studying intercellular adhesion molecule 1 (ICAM1), a cell surface glycoprotein involved in immune response and inflammation. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in various research applications, including Western blotting.ICAM1 plays a crucial role in immune cell adhesion and migration, as well as in the regulation of inflammatory responses. Dysregulation of ICAM1 expression has been implicated in various diseases, including inflammatory disorders, autoimmune conditions, and cancer.
The ICAM1 Polyclonal Antibody enables researchers to detect and analyze ICAM1 expression in different cell types, providing insights into its function and potential therapeutic targets.By using the ICAM1 Polyclonal Antibody, researchers can further unravel the mechanisms underlying immune response modulation and inflammatory pathways, contributing to the development of novel therapeutic approaches for diseases characterized by dysregulated immune function. Unlock the potential of ICAM1 research with this reliable and validated antibody for your immunology and cancer research studies.
Product Name:
ICAM-1/CD54 Rabbit Polyclonal Antibody
SKU:
CAB5597
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-480 of human ICAM-1/CD54 (NP_000192.2).
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
Purification Method:
Affinity purification
Gene ID:
3383
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ICAM-1/CD54 Rabbit pAb (CAB5597) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.5s.