The ICAM1 Polyclonal Antibody (CAB13620) is specifically designed for research involving ICAM1, also known as Intercellular Adhesion Molecule 1, a cell surface glycoprotein involved in immune response and inflammation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it suitable for a variety of research applications.ICAM1 is a critical molecule in the immune system, functioning as a ligand for the integrin LFA-1 and playing a key role in adhesion and activation of leukocytes. It is involved in various physiological processes such as T cell activation, leukocyte recruitment, and immune response to pathogens. The ICAM1 Polyclonal Antibody binds specifically to ICAM1 protein, enabling accurate detection and analysis in different cell types.
Due to its involvement in immune response and inflammation, ICAM1 is a potential target for research in various fields such as immunology, oncology, and inflammatory diseases. Understanding the role of ICAM1 in immune regulation and inflammation can provide valuable insights into the development of therapeutic strategies for conditions like cancer, autoimmune disorders, and chronic inflammatory conditions. The ICAM1 Polyclonal Antibody is a valuable tool for researchers looking to investigate the functions and mechanisms of ICAM1 in different biological contexts.
Product Name:
ICAM-1/CD54 Polyclonal Antibody
SKU:
CAB13620
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-480 of human ICAM-1/CD54 (NP_000192.2).
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
Purification Method:
Affinity purification
Gene ID:
3383
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Raji, using ICAM-1/CD54 antibody (CAB13620) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
![Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Low Endotoxin](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/214503/569409/anti-mouse-icam-1-cd54-be29g1-in-vivo-antibody-low-endotoxin__35728.1673496775.jpg?c=2 "Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Low Endotoxin")
![Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/214502/569388/anti-mouse-icam-1-cd54-be29g1-in-vivo-antibody-ultra-low-endotoxin__83512.1673496755.jpg?c=2 "Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody - Ultra Low Endotoxin")
