IBSP Polyclonal Antibody (CAB16220)
- SKU:
- CAB16220
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | IBSP Polyclonal Antibody |
SKU: | CAB16220 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IBSP (NP_004958.2). |
Sequence: | MKTA LILL SILG MACA FSMK NLHR RVKI EDSE ENGV FKYR PRYY LYKH AYFY PHLK RFPV QGSS DSSE ENGD DSSE EEEE EEET SNEG ENNE ESNE DEDS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BSP; BNSP; SP-II; BSP-II; IBSP |
Positive Sample: | U2OS,U-138MG,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 35kDa |
Observed MW: | 35kDa |
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
Purification Method: | Affinity purification |
Gene ID: | 3381 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |