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IκBα Polyclonal Antibody (CAB23223)

SKU:
CAB23223
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

IκBα Polyclonal Antibody (CAB23223)

The I-B Polyclonal Antibody (CAB23223) is a vital tool for researchers studying the CD300A protein. CD300A is a cell surface molecule that is involved in immune regulation, particularly in inhibiting immune responses. This antibody, produced in rabbits, has high reactivity with human samples and is validated for Western blot applications. By binding to the CD300A protein, this antibody allows for the detection and analysis of CD300A in various cell types, making it perfect for studies in immunology and cancer research.CD300A, also known as an immune inhibitory receptor, plays a crucial role in maintaining immune homeostasis by regulating inflammation and suppressing allergic reactions.

Its importance in modulating immune responses makes it a valuable target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD300A is essential for developing therapies that can manipulate or harness immune function in these disease contexts. The I-B Polyclonal Antibody (CAB23223) is a powerful tool for researchers seeking to explore the role of CD300A in health and disease.

Product Name:IκBα Polyclonal Antibody
Product Code:CAB23223
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Positive Samples:HeLa, Jurkat, NIH/3T3, Mouse thymus, Rat thymus, PC-12

Enables NF-kappaB binding activity and heat shock protein binding activity. Involved in several processes, including cytoplasmic sequestering of NF-kappaB; leukocyte migration involved in inflammatory response; and liver regeneration. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Located in cytosol and nucleus. Part of protein-containing complex. Used to study gastritis; pulmonary emphysema; and sciatic neuropathy. Biomarker of several diseases, including acute necrotizing pancreatitis; alcoholic hepatitis; artery disease (multiple); middle cerebral artery infarction; and toxic shock syndrome. Human ortholog(s) of this gene implicated in several diseases, including childhood-onset asthma; hematologic cancer (multiple); hepatitis B; hepatitis C; and lung disease (multiple). Orthologous to human NFKBIA (NFKB inhibitor alpha).

Immunogen:Recombinant protein of rat IκBα.
Sequence:Email for sequence
Synonyms:RL/IF-1
Calculated MW:35kDa
Observed MW:40kDa

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