The HUS1B Polyclonal Antibody (CAB6817) is a valuable tool for researchers studying the HUS1B protein, a key component of the DNA damage response pathway. This antibody, raised in rabbits, is specifically reactive with human samples and is validated for use in Western blot applications. By binding to the HUS1B protein, this antibody enables the detection and analysis of HUS1B in various cell types, making it an essential tool for studies in DNA repair mechanisms and cancer research.HUS1B is a crucial player in maintaining genome stability by sensing DNA damage and initiating repair processes.
Dysregulation of HUS1B has been implicated in various diseases, including cancer and genetic disorders. Therefore, studying the function and regulation of HUS1B is vital for understanding mechanisms underlying these conditions and developing targeted therapies.Overall, the HUS1B Polyclonal Antibody (CAB6817) is a reliable tool for researchers investigating DNA damage response pathways and the role of HUS1B in human health and disease. Its high specificity and reactivity with human samples make it a valuable asset for studies in molecular biology, oncology, and genetics.
Product Name:
HUS1B Rabbit Polyclonal Antibody
SKU:
CAB6817
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human HUS1B (NP_683762.2).
The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.
Purification Method:
Affinity purification
Gene ID:
135458
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HUS1B antibody (CAB6817) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
