Human XCR1-Strep full length protein-synthetic nanodisc (HDFP856)
- SKU:
- HDFP856
- Size:
- 10μg
- Target:
- XCR1
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human XCR1-Strep Protein |
| SKU: | HDFP856 |
| Size: | 10μg |
| Target: | XCR1 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | CCXCR1; GPR5 |
| Protein Families: | Druggable Genome, GPCR, Transmembrane. |
| Protein Description: | Human XCR1-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | Chemokine signaling pathway, Cytokine-cytokine receptor interaction. |
| Molecular Weight: | The human full length XCR1-Strep protein has a MW of 38.5 kDa |
The protein is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene.
| Uniprot ID: | P46094 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
Related Products
