Human VSTM2L Recombinant Protein (RPPB5138)
- SKU:
- RPPB5138
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96N03
Description
| Product Name: | Human VSTM2L Recombinant Protein |
| Product Code: | RPPB5138 |
| Size: | 10µg |
| Species: | Human |
| Target: | VSTM2L |
| Synonyms: | V-set and transmembrane domain-containing protein 2-like protein, VSTM2L, C20orf102, dJ1118M15.2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | VSTM2L protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl,1mM DTT and 0.1mM PMSF. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMTRPAG HAPWDNHVSG HALFTETPHD MTARTGEDVE MACSFRGSGS PSYSLEIQWW YVRSHRDWTD KQAWASNQLK ASQQEDAGKE ATKISVVKVV GSNISHKLRL SRVKPTDEGS YECRVIDFSD GKARHHKVKA YLRVQPGENS VLHLPEAPPA APAPPPPKPG KELRKRSVDQ EACSL |
V-set and transmembrane domain containing 2 (VSTM2L) is a novel modulator of HN neuroprotective activity. VSTM2L colocalizes with HN in distinct brain areas as well as in primary cultured neurons, where it plays a part in the modulation of neuronal viability. When tested in HN neuroprotection bioassays, VSTM2L acts as a potent antagonist of HN neuroprotective activity. The VSTM2L protein is the first example of a secreted antagonist of HN and may have a role in the modulation of HN biological functions.
VSTM2L Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 205 amino acids (25-204 a.a.) and having a molecular mass of 22.6kDa. VSTM2L is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | VSTM2L: 3 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 20q11.23Cellular Component: cytoplasm; extracellular regionMolecular Function: protein bindingBiological Process: negative regulation of neuron apoptosis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96N03 |
| NCBI GenInfo Identifier: | 18079321 |
| NCBI Gene ID: | 128434 |
| NCBI Accession: | NP_542174.1 |
| UniProt Secondary Accession: | Q96N03,Q5JWZ4, Q5JWZ5, Q8ND45, Q9BR37, E1P5V7 |
| UniProt Related Accession: | Q96N03 |
| Molecular Weight: | 36kD |
| NCBI Full Name: | V-set and transmembrane domain-containing protein 2-like protein |
| NCBI Synonym Full Names: | V-set and transmembrane domain containing 2 like |
| NCBI Official Symbol: | VSTM2L�� |
| NCBI Official Synonym Symbols: | C20orf102; dJ1118M15.2�� |
| NCBI Protein Information: | V-set and transmembrane domain-containing protein 2-like protein |
| UniProt Protein Name: | V-set and transmembrane domain-containing protein 2-like protein |
| UniProt Synonym Protein Names: | |
| Protein Family: | V-set and transmembrane domain-containing protein 2-like protein |
| UniProt Gene Name: | VSTM2L�� |
| UniProt Entry Name: |
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