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Human Urokinase/uPA Recombinant Protein (His tag)

SKU:
RPES6083
Product Type:
Recombinant Protein
Species:
Human
$359
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Description

Product Name:Human Urokinase/uPA Recombinant Protein (His tag)
Product Code:RPES6083
Size:20µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:Urokinase-Type Plasminogen Activator, U-Plasminogen Activator, uPA, PLAU, ATF, BDPLT5, QPD, u-PA, UPA, URK
Mol Mass:47.3 kDa
AP Mol Mass:45 kDa
Tag:C-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Met1-Leu431
Accession:P00749
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.

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