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Human UBE2Q2 Recombinant Protein (RPPB2388)

SKU:
RPPB2388
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q8WVN8
Research Area:
Enzymes
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Description

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Product Name:Human UBE2Q2 Recombinant Protein
Product Code:RPPB2388
Size:10µg
Species:Human
Target:UBE2Q2
Synonyms:Ubiquitin-conjugating enzyme E2 Q2, UBE2Q2, E2 ubiquitin-conjugating enzyme Q2, Ubiquitin carrier protein Q2, Ubiquitin-protein ligase Q2, Ubiquitin Conjugating Enzyme E2Q2, Ubiquitin-conjugating enzyme E2 Q2 isoform1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:UBE2Q2 protein solution (0.5mg/ml) containing Phosphate Buffer Saline (pH7.4), 30% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMSVSGLK AELKFLASIF DKNHERFRIV SWKLDELHCQ FLVPQQGSPH SLPPPLTLHC NITESYPSSS PIWFVDSEDP NLTSVLERLE DTKNNNLLRQ QLKWLICELC SLYNLPKHLD VEMLDQPLPT GQNGTTEEVT SEEEEEEEEM AEDIEDLDHY EMKEEEPISG KKSEDEGIEK ENLAILEKIR KTQRQDHLNG AVSGSVQASD RLMKELRDIY RSQSYKTGIY SVELINDSLY DWHVKLQKVD PDSPLHSDLQ ILKEKEGIEY ILLNFSFKDN FPFDPPFVRV VLPVLSGGYV LGGGALCMEL LTKQGWSSAY SIESVIMQIN ATLVKGKARV QFGANKNQYN LARAQQSYNS IVQIHEKNGW YTPPKEDG

UbiquitinConjugating Enzyme E2Q2 (UBE2Q2) is a protein coding gene which receives ubiquitinfrom the E1 complex and catalyzes its covalent attachment to various proteins. UBE2Q2which is a part of the ubiquitin-conjugating enzyme family is detected inhypopharyngeal head and neck squamous cell carcinoma and in tumor masses.

UBE2Q2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 398 amino acids (1-375a.a.) and having a molecular mass of 45.2kDa.UBE2Q2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:UBE2Q2: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Belongs to the ubiquitin-conjugating enzyme family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 6.3.2.19; Ubiquitin conjugating system; Ligase; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 15q24.2

Molecular Function:ubiquitin-protein ligase activity

UniProt Code:Q8WVN8
NCBI GenInfo Identifier:74751557
NCBI Gene ID:92912
NCBI Accession:Q8WVN8.1
UniProt Secondary Accession:Q8WVN8,Q8N4G6, Q96J08, B7Z3Q2, H3BRG2,
UniProt Related Accession:Q8WVN8
Molecular Weight:38,699 Da
NCBI Full Name:Ubiquitin-conjugating enzyme E2 Q2
NCBI Synonym Full Names:ubiquitin conjugating enzyme E2 Q2
NCBI Official Symbol:UBE2Q2��
NCBI Protein Information:ubiquitin-conjugating enzyme E2 Q2
UniProt Protein Name:Ubiquitin-conjugating enzyme E2 Q2
UniProt Synonym Protein Names:E2 ubiquitin-conjugating enzyme Q2; Ubiquitin carrier protein Q2; Ubiquitin-protein ligase Q2
Protein Family:Ubiquitin-conjugating enzyme
UniProt Gene Name:UBE2Q2��
UniProt Entry Name:UB2Q2_HUMAN

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