Human TRPM7-Strep full length protein-synthetic nanodisc (HDFP1390)
- SKU:
- HDFP1390
- Size:
- 10μg
- Target:
- TRPM7
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human TRPM7-Strep Protein |
| SKU: | HDFP1390 |
| Size: | 10μg |
| Target: | TRPM7 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | ALSPDC, CHAK, CHAK1, LTRPC7, LTrpC-7, TRP-PLIK |
| Protein Families: | Ion Channels: Transient receptor potential. |
| Protein Description: | Human TRPM7-Strep full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length TRPM7-Strep protein has a MW of 212.7 kDa |
This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]
| Uniprot ID: | Q96QT4 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
Related Products
