Human TNFRSF11A Polyclonal Antibody (CAB22547)
- SKU:
- CAB22547
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Human TNFRSF11A Polyclonal Antibody |
SKU: | CAB22547 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-212 of human TNFRSF11A. (NP_003830.1). |
Sequence: | IAPP CTSE KHYE HLGR CCNK CEPG KYMS SKCT TTSD SVCL PCGP DEYL DSWN EEDK CLLH KVCD TGKA LVAV VAGN STTP RRCA CTAG YHWS QDCE CCRR NTEC APGL GAQH PLQL NKDT VCKP CLAG YFSD AFSS TDKC RPWT NCTF LGKR VEHH GTEK SDAV CSSS LPAR KPPN EPHV YLP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1; TRANCE-R; Human TNFRSF11A |
Positive Sample: | C2C12 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, external side of plasma membrane, plasma membrane |
Calculated MW: | 66kDa |
Observed MW: | 100kDa |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Purification Method: | Affinity purification |
Gene ID: | 8792 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |