Human TNFα Recombinant Protein (His Tag) (HDPT0060)
- SKU:
- HDPT0060
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human TNFα Recombinant Protein (His Tag)
| Description: | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
| Product name: | Human TNFα Recombinant Protein (His Tag) |
| Synonyms: | DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα |
| Type: | protein |
| Size: | 50 µg |
| Name: | TNFα |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | TNFα（Val77-Leu233）+6×His tag |
| Gene ID: | 7124 |
| Uniprot: | P01375 |
| Molecular Weight: | 18.1 kDa |
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