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Human Th1/Th2/Th17 Array (34 targets) (SARB0071)

SKU:
SARB0071
Product Type:
Protein Array
Analytes:
CD30 (TNFRSF8)
CD40 Ligand (TNFSF5)
CD40 (TNFRSF5)
GCSF
GITR (TNFRSF18)
GM-CSF
IFN-gamma
IL-1 beta (IL-1 F2)
IL-1 R1
IL-1 R2
IL-2
IL-4
IL-5
IL-6
IL-6 R
IL-10
IL-12 p40
IL-12 p70
IL-13
IL-17A
IL-17F
IL-17 RA
IL-21
IL-21 R
IL-22
IL-23
IL-28A (IFN-lambda 2)
MIP-3 alpha (CCL20)
gp130
TGF beta 1
TGF beta 3
TNF alpha
TNF beta (TNFSF1B)
TRANCE (TNFSF11)
Reactivity:
Human
Applications:
Multiplex Array
€679 - €1,369
Frequently bought together:

Description

system_update_altDatasheet

Human Th1/Th2/Th17 Array (34 targets) (SARB0071)

The Human TH1/TH2/TH17 Array (34 Targets) (SARB0071) is a powerful tool for researchers studying immune responses and cytokine signaling pathways. This array allows for the simultaneous detection and quantification of 34 key cytokines, chemokines, and growth factors involved in TH1, TH2, and TH17 immune responses.With high sensitivity and specificity, this array provides valuable insights into the complex interplay of cytokines in immune-mediated diseases such as autoimmune disorders, inflammatory conditions, and cancer. Researchers can use this array to profile cytokine expression levels in various cell types and biological samples, helping to identify potential biomarkers and therapeutic targets.

The Human TH1/TH2/TH17 Array (34 Targets) is a reliable and efficient tool for exploring the dynamic nature of immune responses and uncovering novel insights into the molecular mechanisms underlying immune regulation. Whether studying the pathogenesis of diseases or evaluating the efficacy of immunomodulatory therapies, this array offers a comprehensive and high-throughput solution for cytokine profiling in research settings.

Product Sku:SARB0071
Size:2, 4, or 8
Species Detected:Human
Number of Targets Detected:34
Gene Symbols:CCL20, CD40, CD40LG, CSF2, CSF3, IFNG, IFNL2, IL10, IL12A, IL12B|IL13, IL17A, IL17F, IL17RA, IL1B, IL1R1, IL1R2, IL2, IL21, IL21R, IL22, IL23A, IL4, IL5, IL6, IL6R, IL6ST, LTA, TGFB1, TGFB3, TNF, TNFRSF18, TNFRSF8, TNFSF11
Compatible Sample Types:Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Lysates
Design Principle:Sandwich-based
Method of Detection:Chemiluminescence
Pathway:NFkB Signaling
Quantitative/Semi-Quantitative:Semi-Quantitative
Solid Support:Membrane
Suggested Application(s):Multiplexed Protein Detection; Detection of Relative Protein Expression; Detecting Patterns of Cytokine Expression; Biomarker/ Key Factor Screening; Identifying Key Factors; Confirming a Biological Process
Storage/Stability:For best results, store the entire kit frozen at -20°C upon arrival. Stored frozen, the kit will be stable for at least 6 months which is the duration of the product warranty period.
Once thawed, store array membranes and 1X Blocking Buffer at -20°C and all other reagents undiluted at 4°C for no more than 3 months.
Hover over target for more information
CD30 (TNFRSF8)
  • Gene Symbol: CD30
  • Gene ID: 943
  • Accession #: P28908
CD40 Ligand (TNFSF5)
  • Gene Symbol: CD40LG
  • Gene ID: 959
  • Accession #: P29965
CD40 (TNFRSF5)
  • Gene Symbol: CD40
  • Gene ID: 958
  • Accession #: P25942
GCSF
  • Gene Symbol: CSF3
  • Gene ID: 1440
  • Accession #: P09919
GITR (TNFRSF18)
  • Gene Symbol: TNFRSF18
  • Gene ID: 8784
  • Accession #: Q9Y5U5
GM-CSF
  • Gene Symbol: CSF2
  • Gene ID: 1437
  • Accession #: P04141
IFN-gamma
  • Gene Symbol: IFNG
  • Gene ID: 3458
  • Accession #: P01579
IL-1 beta (IL-1 F2)
  • Gene Symbol: IL1B
  • Gene ID: 3553
  • Accession #: P01584
IL-1 R1
  • Gene Symbol: IL1R1
  • Gene ID: 3554
  • Accession #: P14778
IL-1 R2
  • Gene Symbol: IL1R2
  • Gene ID: 7850
  • Accession #: P27930
IL-2
  • Gene Symbol: IL2
  • Gene ID: 3558
  • Accession #: P60568
IL-4
  • Gene Symbol: IL4
  • Gene ID: 3565
  • Accession #: P05112
IL-5
  • Gene Symbol: IL5
  • Gene ID: 3567
  • Accession #: P05113
IL-6
  • Gene Symbol: IL6
  • Gene ID: 3569
  • Accession #: P05231
IL-6 R
  • Gene Symbol: IL6R
  • Gene ID: 3570
  • Accession #: P08887
IL-10
  • Gene Symbol: IL10
  • Gene ID: 3586
  • Accession #: P22301
IL-12 p40
  • Gene Symbol: IL12B
  • Gene ID: 3593
  • Accession #: P29460
IL-12 p70
  • Gene Symbol: IL12A
  • Gene ID: 3592
  • Accession #: P29459
IL-13
  • Gene Symbol: IL13
  • Gene ID: 3596
  • Accession #: P35225
IL-17A
  • Gene Symbol: IL17A
  • Gene ID: 3605
  • Accession #: Q16552
IL-17F
  • Gene Symbol: IL17F
  • Gene ID: 112744
  • Accession #: Q96PD4
IL-17 RA
  • Gene Symbol: IL17RA
  • Gene ID: 23765
  • Accession #: Q96F46
IL-21
  • Gene Symbol: IL21
  • Gene ID: 59067
  • Accession #: Q9HBE4
IL-21 R
  • Gene Symbol: IL21R
  • Gene ID: 50615
  • Accession #: Q9HBE5
IL-22
  • Gene Symbol: IL22
  • Gene ID: 50616
  • Accession #: Q9GZX6
IL-23
  • Gene Symbol: IL23A
  • Gene ID: 51561
  • Accession #: Q9NPF7
IL-28A (IFN-lambda 2)
  • Gene Symbol: IFNL2
  • Gene ID: 282616
  • Accession #: Q8IZJ0
MIP-3 alpha (CCL20)
  • Gene Symbol: CCL20
  • Gene ID: 6364
  • Accession #: P78556
gp130
  • Gene Symbol: Il6st
  • Gene ID: 3572
  • Accession #: P40189
TGF beta 1
  • Gene Symbol: TGFB1
  • Gene ID: 7040
  • Accession #: P01137
TGF beta 3
  • Gene Symbol: TGFB3
  • Gene ID: 7043
  • Accession #: P10600
TNF alpha
  • Gene Symbol: TNF
  • Gene ID: 7124
  • Accession #: P01375
TNF beta (TNFSF1B)
  • Gene Symbol: LTA
  • Gene ID: 4049
  • Accession #: P01374
TRANCE (TNFSF11)
  • Gene Symbol: TNFSF11
  • Gene ID: 8600
  • Accession #: O14788
  • Easy to use
  • No specialized equipment needed
  • Compatible with nearly any liquid sample
  • Proven technology
  • Highly sensitive (pg/ml)
  • Sandwich ELISA specificity
  • Higher density than ELISA, Western blot or bead-based multiplex
  • Human Th1/Th2/Th17 Antibody Array C1 Membranes
  • Blocking Buffer
  • Wash Buffer 1
  • Wash Buffer 2
  • Biotinylated Detection Antibody Cocktail
  • Streptavidin-Conjugated HRP
  • Detection Buffer C
  • Detection Buffer D
  • Lysis Buffer
  • 8-Well Incubation Tray
  • Plastic Sheets
  • Array Templates

Other Materials Required

  • Pipettors, pipet tips and other common lab consumables
  • Orbital shaker or oscillating rocker
  • Tissue Paper, blotting paper or chromatography paper
  • Adhesive tape or Saran Wrap
  • Distilled or de-ionized water
  • A chemiluminescent blot documentation system , X-ray Film and a suitable film processor, or another chemiluminescent detection system.
1.Block membranes
2.Incubate with Sample
3.Incubate with Biotinylated Detection Antibody Cocktail
4.Incubate with HRP-Conjugated Streptavidin
5.Incubate with Detection Buffers
6.Image with chemiluminescent imaging system
7.Perform densitometry and analysis

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