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Human TdT / DNA nucleotidylexotransferase ELISA Kit

SKU:
HUFI01505
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P04053
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
DNTT, DNA nucleotidylexotransferase, TDT, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling
€599
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Description

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Human TdT / DNA nucleotidylexotransferase ELISA

TdT / DNA nucleotidylexotransferase encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. TdT / DNA nucleotidylexotransferase is expressed in pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Diseases associated with TdT / DNA nucleotidylexotransferase include Lymphoblastic Lymphoma and Myeloid Sarcoma.