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Human STING1 Full-Length Bioactive Membrane Protein (HDFP021)

SKU:
HDFP021
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q86WV6
$1,667

Description

system_update_altDatasheet
Product nameHuman STING1 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP021
Product CategoryFull Length Transmembrane Proteins
Target:STING1
Uniprot:Q86WV6
Description:Human STING1 full length protein-synthetic nanodisc
Molecular Weight:The human full length STING1 protein has a MW of 42.2 kDa
Protein Family:
Protein Pathways:Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING; STING-beta; TMEM173
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Delivery:3-4 weeks
UsageResearch use only

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