Human STEAP2-Strep full length protein-synthetic nanodisc (HDFP785)
- SKU:
- HDFP785
- Size:
- 10μg
- Target:
- STEAP2
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human STEAP2-Strep Protein |
| SKU: | HDFP785 |
| Size: | 10μg |
| Target: | STEAP2 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | IPCA1; PCANAP1; PUMPCn; STAMP1; STMP |
| Protein Families: | Transmembrane. |
| Protein Description: | Human STEAP2-Strep full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length STEAP2-Strep protein has a MW of 56.1 kDa |
A member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
| Uniprot ID: | Q8NFT2 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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