Description
Product Name: | Nanodisc Human SMO-Strep Protein |
SKU: | HDFP1189 |
Size: | 10μg |
Target: | SMO |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | CRJS, FZD11, Gx, PHLS, SMOH |
Protein Families: | ES Cell Differentiation/IPS , Transmembrane, Stem cell relevant signaling – DSL/Notch pathway, Druggable Genome. |
Protein Description: | Human SMO-Strep full length protein-synthetic nanodisc |
Protein Pathways: | GPCRDB Other, Hedgehog Netpath 10, Hedgehog Netpath 10, Apoptosis, Cancer, Notch. |
Molecular Weight: | The human full length SMO-Strep protein has a MW of 86.4 kDa |
The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]
Uniprot ID: | Q99835 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |