Human SEC22B Recombinant Protein (RPPB4609)
- SKU:
- RPPB4609
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O75396
Description
| Product Name: | Human SEC22B Recombinant Protein |
| Product Code: | RPPB4609 |
| Size: | 20µg |
| Species: | Human |
| Target: | SEC22B |
| Synonyms: | SEC22 Vesicle Trafficking Protein Homolog B (S. Cerevisiae) Gene/Pseudogene, SEC22 Vesicle Trafficking Protein-Like 1 (S. Cerevisiae), ER-Golgi SNARE Of 24 KDa, SEC22L1, ERS-24. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The SEC22B solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 2M Urea, 0.15M NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSM LPLAAS MQEDEQSGRD LQQYQSQAKQ LFRKLNEQSP TRCTLEAGAM TFHYIIEQGV CYLVLCEAAF PKKLAFAYLE DLHSEFDEQH GKKVPTVSRP YSFIEFDTFI QKTKKLYIDS RARRNLGSIN TELQDVQRIM VANIEEVLQR GEALSALDSK ANNLSSLSKK YRQDAKYLNM RSTYA |
Vesicle-trafficking protein SEC22b precursor (SEC22B) is a member of the synaptobrevin family. SEC22B forms a complex with SNARE and it is believed to have a role in the ER-Golgi protein trafficking. SEC22B has a strong similarity to the mouse and Chinese hamster proteins.
SEC22B Human Recombinant produced in E. coli is a single polypeptide chain containing 205 amino acids (14-194) and having a molecular mass of 23.3 kDa.SEC22B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SEC22B: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. Belongs to the synaptobrevin family. |
| UniProt Protein Details: | Protein type:Vesicle; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q21.1 Cellular Component: Golgi membrane; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; integral to membrane; ER-Golgi intermediate compartment; melanosome Molecular Function:protein binding; syntaxin binding Biological Process: ER to Golgi vesicle-mediated transport; protein transport; positive regulation of protein catabolic process; regulation of organelle organization and biogenesis |
| NCBI Summary: | The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins.[provided by RefSeq, Sep 2009] |
| UniProt Code: | O75396 |
| NCBI GenInfo Identifier: | 317373544 |
| NCBI Gene ID: | 9554 |
| NCBI Accession: | O75396.4 |
| UniProt Related Accession: | O75396 |
| Molecular Weight: | |
| NCBI Full Name: | Vesicle-trafficking protein SEC22b |
| NCBI Synonym Full Names: | SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) |
| NCBI Official Symbol: | SEC22B�� |
| NCBI Official Synonym Symbols: | ERS-24; SEC22L1�� |
| NCBI Protein Information: | vesicle-trafficking protein SEC22b |
| UniProt Protein Name: | Vesicle-trafficking protein SEC22b |
| UniProt Synonym Protein Names: | ER-Golgi SNARE of 24 kDa; ERS-24; ERS24; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1 |
| Protein Family: | Vesicle-trafficking protein |
| UniProt Gene Name: | SEC22B�� |
| UniProt Entry Name: | SC22B_HUMAN |
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