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Human S1PR5-Strep full length protein-synthetic nanodisc (HDFP1187)

SKU:
HDFP1187
Size:
10μg
Target:
S1PR5
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249

Description

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Product Name:Nanodisc Human S1PR5-Strep Protein
SKU:HDFP1187
Size:10μg
Target:S1PR5
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Protein Families:GPCR, Transmembrane, Druggable Genome.
Protein Description:Human S1PR5-Strep full length protein-synthetic nanodisc
Protein Pathways:S1P Signaling.
Molecular Weight:The human full length S1PR5-Strep protein has a MW of 41.8 kDa

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]

Uniprot ID:Q9H228
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

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