null

Human S1PR1-Strep full length protein-synthetic nanodisc (HDFP1183)

SKU:
HDFP1183
Size:
10μg
Target:
S1PR1
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Nanodisc Human S1PR1-Strep Protein
SKU:HDFP1183
Size:10μg
Target:S1PR1
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1
Protein Families:GPCR, Transmembrane, Druggable Genome.
Protein Description:Human S1PR1-Strep full length protein-synthetic nanodisc
Protein Pathways:GPCRDB Other, S1P Signaling, Small ligand GPCRs, Angiogenesis, Angiogenesis, G-Protein Coupled Receptors Signaling Pathway.
Molecular Weight:The human full length S1PR1-Strep protein has a MW of 42.8 kDa

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Uniprot ID:P21453
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

Related Products