Human S100A3 Recombinant Protein (RPPB4554)
- SKU:
- RPPB4554
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P33764
Description
| Product Name: | Human S100A3 Recombinant Protein |
| Product Code: | RPPB4554 |
| Size: | 10µg |
| Species: | Human |
| Target: | S100A3 |
| Synonyms: | S100-A3, S-100E, S100 calcium-binding protein A3, S100E, S-100A3, Protein S100-A3, Protein S-100E, S100A3. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | S100A3 protein at 1mg/ml in 20mM Tris-HCl buffer (pH 8.0), 20% glycerol, 2mM DTT and 0.2M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MARPLEQAVA AIVCTFQEYA GRCGDKYKLC QAELKELLQK ELATWTPTEF RECDYNKFMS VLDTNKDCEV DFVEYVRSLA CLCLYCHEYF KDCPSEPPCS Q |
S100A3 is part of S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm/nucleus of a broad range of cells, and takes part in the regulation of several cellular processes such as cell cycle progression and differentiation. S100A3 has the largest number of cysteines of all S100 proteins. S100A3 has high affinity for Zinc, and is widely expressed in human hair cuticle.
S100A3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 121 amino acids (1-101) and having a molecular mass of 13.9kDa.The S100A3 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | S100A3: Binds both calcium and zinc. Probably binds 2 zinc ions per molecule. May be involved in calcium-dependent cuticle cell differentiation and hair shaft formation. Belongs to the S-100 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; nucleolus Molecular Function:zinc ion binding; calcium ion binding |
| NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P33764 |
| NCBI GenInfo Identifier: | 464729 |
| NCBI Gene ID: | 6274 |
| NCBI Accession: | P33764.1 |
| UniProt Secondary Accession: | P33764,Q6FGE4, D3DV51, |
| UniProt Related Accession: | P33764 |
| Molecular Weight: | 101 |
| NCBI Full Name: | Protein S100-A3 |
| NCBI Synonym Full Names: | S100 calcium binding protein A3 |
| NCBI Official Symbol: | S100A3�� |
| NCBI Official Synonym Symbols: | S100E�� |
| NCBI Protein Information: | protein S100-A3; S100 calcium-binding protein A3 |
| UniProt Protein Name: | Protein S100-A3 |
| UniProt Synonym Protein Names: | Protein S-100E; S100 calcium-binding protein A3 |
| Protein Family: | Protein |
| UniProt Gene Name: | S100A3�� |
| UniProt Entry Name: | S10A3_HUMAN |
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