Description
Product Name: | Nanodisc Human PTH2R-Strep Protein |
SKU: | HDFP1175 |
Size: | 10μg |
Target: | PTH2R |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | PTHR2 |
Protein Families: | GPCR, Transmembrane, Druggable Genome. |
Protein Description: | Human PTH2R-Strep full length protein-synthetic nanodisc |
Protein Pathways: | GPCRDB Class B Secretin-like. |
Molecular Weight: | The human full length PTH2R-Strep protein has a MW of 62.2 kDa |
The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Uniprot ID: | P49190 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |