Human PTGER4 Full-Length Bioactive Membrane Protein (HDFP078)
- SKU:
- HDFP078
- Product Type:
- Recombinant Protein
- Protein Type:
- Full-Length Bioactive Membrane Protein
- Species:
- Human
- Uniprot:
- P35408
Frequently bought together:
Description
system_update_altDatasheet
Product name | Human PTGER4 full length protein-synthetic nanodisc |
Size: | 10ug |
Product SKU: | HDFP078 |
Product Category | Full Length Transmembrane Proteins |
Target: | PTGER4 |
Uniprot: | P35408 |
Description: | Human PTGER4 full length protein-synthetic nanodisc |
Molecular Weight: | The human full length PTGER4 protein has a MW of 53.1 kDa |
Protein Family: | Druggable Genome, GPCR, Transmembrane |
Protein Pathways: | Neuroactive ligand-receptor interaction |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Synonyms: | EP4; EP4R |
Expression System: | HEK293 |
Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Background: | The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008] |
Delivery: | 3-4 weeks |
Usage | Research use only |